404 errors after installing and configuring defender

HELP! I have a multisite setup. After I downloaded and finished doing all the defender recommendations, I now have a bunch on 404 errors on my sites. Deactivating defender does not help.
1. when I go to my sites and click on the site's dashboard I get a 404 error
2. on my site's inside pages all have 404 error (http://homehitch.com/)

My Main site is http://www.globalgroupus.com/ I've already granted support access if you need it. This is bad! My client is proofing the site.