A BuddyPress Multi Network and New Blog Template plugin marriage?

Hello,

I'm working on a new BuddyPress Multi Network.

This is my question (It's a mouthful...):

Do you foresee any obvious issues using a cloned frontpage site of a Buddypress enabled multi-site as the child-site template for a BuddyPress Multi Network?

I'm trying to decide if I can just speedily clone the frontpage site or need to rebuild the original theme on a sub-site to use for cloning to sub-sites.

Should I disable Buddypress and disable ( BP_ENABLE_MULTIBLOG defined true) before I clone? Since it is already the same theme and Buddypress enabled, it sounds like the way to go.

I'm considering using the "New Blog Template" plugin to clone.
(https://premium.wpmudev.org/project/new-blog-template/)

...and for the multi-Buddypress network plugin:
(http://buddydev.com/plugins/buddypress-multi-network/)

I'm also posting this question to http://buddydev.com/.

Cheers,
Terry