Activity Comments

I just installed Comments Plus and have a couple of questions about it.

1) I'm also using Ultimate Facebook and a non-WPMU plug-in called "Buddy Stream" that populates the Activity Streams with content from various social media sites. Should I be using one Facebook/Twitter App Keys for all of these plugins, or should I be creating a unique App Key for each plugin?

1) Does Comments Plus only work with Blog Comments or can I add the hooks and make it work with Activity Stream Comments as well? Would make them a lot more valuable.