Any problems with WordPress 3.5?

I am waiting to see what problems are popping up with wordpress 3.5 before updating, is anyone having any difficulty?

There seemed to be several issues being solved just prior to the release and I am skeptical about them being adequately fixed.

Folks online are reporting problems creating new posts, adding media and with tags; deactivating all plugins and reactivating them one at a time until they all check out or fail can be a real pain in the bottom.

Any WPMU Dev reports of problems?