I am currently using OpenCart as a shopping cart for my digital products. It's worked quite well for a number of years. However, I'm contemplating moving it all to my main WordPress site, because it seems to make sense to me to have a combined "customer/subscriber" base - one place to login, one set of people to manage for mailing lists, etc.
As far as WPMU goes, I currently have Membership, eNewsletter, Google Analytics+, Slide-In, Q&A, Wiki, plus some other specialized plugins to just make my life easier. All in all 33 active plugins. Will Marketpress eCommerce be too much to hope for? This is a "self-hosted" server on Digital Ocean, so I have no problem bumping the specs if necessary.
I'm just wondering if this looks to be asking for trouble.