Best Combo of Plugins for...

I am building a membership site, where membership is free, but I want to get some detailed demographic data, that I want to then use to customize and filter my mailing list based on the custom user registration data I get.

The members will get access to member only content and be automatically in a newsletter list which can be filtered into subgroups based on their data.

eg I ask for gender in the user registration via some membership plugin, give access to certain content to members, and send an html newsletter blast to members who are women only.

I dont want to export my membership list to a newsletter - I'd rather it be all done together. Possible?