Buddypress & wpmu themes, all compatible?

New member seeks to basic understanding!

Hi all - I love the stuff I'm seeing on this site but I'm not sure how it all fits together. For instance, Buddypress seems like a pretty awesome feature...it would seem kind of bummer to build a site that wouldn't at least allow that functionality. But I'm unsure how it works...

1. Can I grab the Edublogs theme (looks great) and slap on Buddypress? Or is the integration intense / impossible.

2. I see several BuddyPress themes, obviously....which make me suspect that Buddypress is kind of intense and perhaps it's best not to bother w/the idea unless you start with a Buddypress theme?

Thanks!

Ryan