Can WPMU or BuddyPress have a subdomain that is not under the network?

Could I create a WPMU or BuddyPress network and have it using subdomains, but for one or more subdomains have them not in the network but be separate WP installs or static HTML sites?

All sites in a buddy press network:
Subdomains not in the network:
• pointed to a separate single non network WP install
• pointed to and serving a static html website?