Chaning Multiple-Database setting in wp-config.php

I got the multi-db plugin working on my site, and I will be writing up much needed and sought after instructions shortly, my questions is pretty simple. Everything is working well, but does one need to change
wp-config define( "WP_USE_MULTIPLE_DB", false );
wp-config define( "WP_USE_MULTIPLE_DB", true );

in the wp-config.php file, or does this become redundant all even obsolete given the code in the multi-db plugin?