Conflicting Themes in WordPress Multisite configuration

I used Oxygen for my site builder at my multisite I have another site as part of that multisite configuration, that is using CoursePro. After lots of trial and error, I discovered that my Oxygen plugin was causing the CoursePro theme not to work correctly on my site. Is there a way to configure multisite’s so that each site has it’s own discrete theme configuration? There probably is, but while I am an experienced WordPress guy, I’m just learning and starting to use Multisite. Thank you in advance.