I am with "Just Host" and they allow me to have all my domains as individual sites. (see screenshot)
In the cpanel they are all under the musicwise root domain as a subdomain:
eg. judiegade.musicwise.com.au but for all intents and purposes, they are their own URL to the public (as above)
Now I have just been told that I cannot install multi-site! My hosting is up in October and I have to launch MusicWise SOON but would like the flexibility of WP multi-user (for obvious reasons).