Defender needs over 100mb of memory?

I got this error from Defender when I tried to configure lockouts:
FATAL ERROR: ALLOWED MEMORY SIZE OF 75497472 BYTES EXHAUSTED (TRIED TO ALLOCATE 83 BYTES) IN /HOME/NEWMEMBERWEBSITE/PUBLIC_HTML/WP-INCLUDES/WP-DB.PHP ON LINE 1841

So I had my server support increase the limit, but then I got this:
FATAL ERROR: ALLOWED MEMORY SIZE OF 96468992 BYTES EXHAUSTED

They suggested I contact WPMUDEV since we're talking about over 100mb of memory.

I haven't had this issue before. Ideas?