Directory and Genesis framework: Do they play nice?

Just wondering if anyone has experience with Directory working within a child theme on the Genesis framework? I'm planning to use Directory and Affiliates and possibly Membership on one install of a Genesis theme. I tried playing with Directory on the Lucid theme from Elegant Themes and the ePanel from ET seemed to make things more difficult than easier.

I'd hate to run into that again, especially after paying for Genesis (which I have not yet) so any user experience would be helpful in making my decision.

Possible child theme for Genesis I'm considering: Metro (if that helps at all).

Thanks so much for any previous user experiences anyone can share!