Does Defender potentially cause indexing issues with Google?

Hi Gurus,

I’ve never used Defender before, so I thought I’d try it out.

I’m getting weird responses from various online tools that I normally have no problem with.

When I submit my website to it says it can’t fetch the URL

When I submit to it also says it can’t access the site.

The google PageSpeed insights plugin can’t run reports on my site.

Has anyone every reported issues like this when using Defender? Thanks!