Does supporter-plugins.php clash with plugin-manager?

A couple of hours ago I realized that any of the plugins that were set to be available to all users would deactivate automatically when you click on them.

I then removed the supporter-plugins.php and everything is fine.

I still have the plugins-manager installed and cant seem to see any difference.

Does the plugin-manager replace the supporter-plugins.php or do I need both?

Thanks,

George