I have a problem with domain mapping. When trying to enter /wp-admin on the mapped domain, it redirects me to domain.tld/usr/qlof/blogdir/wp-admin. Going to /wp-login.php and being redirected from there works, so I can still enter the admin panel.
I originally thought that this was an issue with my caching plugin so I turned it off and even switched from QuickCache to WP Super Cache, but the issue remains. I'm not 100% confident that it is due to the domain mapping plugin, but it's my best guess since the error is appearing on a mapped domain.