E-Newsletter vs Subscribe by EMail

Hello WPMUdev's

I have read the description from the two plugins. But I can still not see exactly which is the right one for which case. Or should I use both of them in tandem? Do they work together?

So can you give me an idea, which one is more modern, more diverse, more easy, more professional, which one works best with other plugins i have installed? How are they different? Just everything which helps me to make a decision..

Thank you very much and greetings
Marc