Failed to send test email, please check outgoing settings

I am using e-newsletter and has sent an email last week and it was fine. But now I get the error

Failed to send test email! - Please check your outgoing email settings and server config to see if selected ports are open. Error details: The following From address failed: alyssa@pileofabric.com : MAIL not accepted from server,421,4.7.0 Try again later, closing connection. (MAIL) kz3sm29904241obb.6 - gsmtp
SMTP server error: 4.7.0 Try again later, closing connection. (MAIL) kz3sm29904241obb.6 - gsmtp

SMTP server error: 4.7.0 Try again later, closing connection. (MAIL) kz3sm29904241obb.6 - gsmtp

I never made changes to my settings and I am using a gmail.