Formatting not saving in upfront


When I save the way I want the lower portion of the site in upfront to be formatted the way i want it shows correct only in upfront. When you go to the live site things are not center and do not place where they are located in upfront. I have reset the cache on my browser as well as in upfront. My server has caching tuned off as well. It is doing an issue similar to this with responsive too. There is a large amount of spacing on the bottom of these regions on live and in upfront it does not. Thanks