Help Getting started

Hi

I am now totally lost with my mu install I can not get any of my websites working properly, the mu site i wanted to create based on edublogs site has had to be sidelined and an external host created as a back up.

All my other sites created pre MU are now down as I cant get either multi-domains or domain-mapping plugins working properly.

I have asked psek for help as i have had to now rebuild 3 websites now - 1 in particular is 700 pages + and over 3 years of work its took me 3 days !

surely I am doing something wrong but i cant find the problem nor the solution

HELP !!