Hosting media (images) on S3 or similar

Hi team!

I'm investigating the best options for hosting/offloading media (images) on an Amazon S3 account, or similar. I can see there's a plugin called Offload S3 which seems to be the goods, but can't find any conclusive information around how well this will work with Smush Pro. I can also see there have been feature requests for Smush to include the ability to offload images to S3 - but not sure where this is at.

So... is there an ideal plugin that is known to work well with Smush in order to accomplish this, or are there features in Smush that I'm not aware of to do this? OR... is there a better way?

Thanks so much for your help!