How to i Change the over all theme colors?

I will like to change all use of #5ebf6b to #e0861a
and #645191 to #404041

When I go into the upfornt I see the theme colors: that need to be change to.

Normal you will do this in childtheme but that i cant with upfront.

http://screencast.com/t/TF4vYmMrRt