How to increase number of databases after multi-db established

Please clarify the process of going from 16 databases to 4096. It is my understanding reading through the forums that you need to merge back to 1 and then start over. We have now tested the process with 16 with our combination of plugins and we finally have everything working well. Now it is time to set up the 4096. I did not see any instructions regarding the required process to go from one level to the next. Please clarify. Thank you.