I think I need to delete some old, large files. Is It Safe?

I formerly used a wordpress back up plugin which saved backup files on my site's shared servers. Now, my current back up program, Updraft, is unable to save these large old backup files, so I would like to delete them. I am still uncomfortable with deleting files that contain data which I don't fully understand. I have attached a screenshot of the large files which I no longer need. Are there any that I should not delete?