I'm getting a 404 -

I'm getting a 404 - http://f.cl.ly/items/3n0V241y1C10271i2m1H/Image%202016-02-09%20at%204.19.45%20PM.png - Seemingly originating from custompress. I also have problems where custom press admin columns on post types are not showing up anymore. Any idea what might be wrong?