Install of the Multi Domains Plugin

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Warning: include_once() [function.include]: Failed opening 'C:\Users\Dave\Desktop\50 Instant Wordpress Instances\3\3\InstantWP_4.2\iwpserver\htdocs\wordpress/wp-content/sunrise.php' for inclusion (include_path='.;C:\Users\Dave\Desktop\50 Instant Wordpress Instances\3\3\InstantWP_4.2\iwpserver\server\php\PEAR') in C:\Users\Dave\Desktop\50 Instant Wordpress Instances\3\3\InstantWP_4.2\iwpserver\htdocs\wordpress\wp-includes\ms-settings.php on line 18
Multisite only works without the port number in the URL.