Is it possible to trigger a PopUp when a user click on a hypertext link?

Hi,

One of my clients want to do something on her subsite.
She wants that the visitors of her site click on some part of content and when they do that one PopUp is triggered with some content.
Her idea would be to create 8 different PopUps. Each one would be triggered when the visitors click on a hypertext link.

How can she do that? Is PopUp the best WPMUdev plugin to achieve this? Any other one?

Thanks!