Jetpack photon vs Amazon S3-Cloudfront

Looking for some general advice.

We're a non-profit, and we're now using your SMUSH plugin (& a few more).

We are photography.org, and so deal with thousands of images. (Right now, it's about 22,000.)

We are using Amazon S3 / Cloudfront, and the WP S3 Upload plugin. It all works well enough.

Here's my question, after reading your "Top CDN Services" article: would we benefit from adding JetPack / Photon?

Can they work together, or is it either/or? Does Photon have storage limits?

And, of course, which/what would you recommend?

Thanks for your help and advice!