lightBox , ColorBox , FancyBox , Thickbox

Hi, i have been dazzled by different types of lightBox that you can use, which one is best if i want to have a grid based page with multiple content each presented in a separate box,
each box will have a main feature image, another images that slide auto,
title and few lines of description,
pop up, some transition effects .
i also need a way for an end user to enter all this info and upload pic for each box