Maintenance Mode Plugins Vs. wpmudev's holder plugin

I have a maintenance mode plugin that is outside of wpmudev and when I try to save certain settings within network settings, it does not save. For example, the upload total size of files, enable administration menus, and update all sites options, I cannot save the changes for these. Is it because of the maintenance mode plugin being active? Will the "Holder" plugin be a better option for this?
Thank you
Andrew