I've just uploaded a beta version of the new Multi-DB release. Feel free to give it a go and report back.
Also, moving forward I'm going to start numbering releases according to the current version of WPMU. So for example, this release will be 2.6. Any releases between versions of WPMU will have the third number bumped. So basically always look at the first two numbers of the version to determine which version of WPMU the particular version of Multi-DB is compatible with.