Multi-DB and Various Plugins


I'm planning ahead for a possible migration to Multi-DB. I understand that some WPMU Dev plugins have instructions for global tables. But what about various other (non-WPMU Dev) plugins (any variety of plugins from Widget Logic to Login Lockdown and dozens more). If I'm using other plugins and I split off to a Multi-DB situation, will I have issues with those plugins (or some of them)? Is there a way to see which plugins use global tables or otherwise need special Multi-DB love?