Multisite Admin Massive {Get} Requests

I am running a network of blogs, currently about to break 1,000 all on subdomains.

My question is the following:
I am using Multi-DB with 256 Databases (there might be some issues with the configuration, and it is being troubleshot currently in another ticket).

When I access the wp-admin area of a subdomain blog, I notice that I have close to 700 requests being pulled. This just seems a little off.

Anyone else having this issue?
Anyone else solve it?