Multisites Service


I'd like to start and build a serious multisite service (free and paid levels) that will be an extension of a bloggers membership site. I see there's a lot of great tools and plugins available and all this creates good mind sparkles but is there a kind of blueprint, or a mu stater kit suggested to start with, available or that would suggest what to use in what you provide to start and grow a successful MU site as what I want to create?

Thanks & Regards,