Networks of Multisites and WPMU plugin compatibility

I am going to make a Network of Networks, or Multi-Site of Multi-Site.

I can choose from: Networks+, Multi-Networks, and Networks for Wordpress. Each of them have their own unique features, but really I just want maximum compatibility.

1. What do you think is the best for WPMU plugin compatibility?
2. What have you found are the major differences in the ability of the network type of plugins?

Anybody feel free to give your opinions!