Optimizing My Site's Plugins Correctly

Hi, I have several of your plugins installed on this site and I believe I may have too many..the site is SUPER SLOW! It recently has started taking 45-60 secs to upload an image and when it completes there are 4-5 copies also uploaded. I have Hummingbird, Branding, and several others but believe it may be overkill.

Can someone who knows the best combination and use case optimization for a high traffic, lots of media blog style membership site? I have to speed things up or client is going to get upset, and I do like your plugins...just need help optimizing them asap please. Thank you.