P2 theme can't connect to server

On newly installed non-multisite, I get "whoops, looks like you are not connected to server...", when trying to update status, using the P2 theme. This was working until I installed WP Better Security and changed my DB table prefix.

When I first had WP BS change the prefix, I was thrown all the way back to the install page, but then I manually changed the default table prefix in wp-config.php. This enabled the site to run. All looked good until I tried to post. So there still seems to be a connected issue.

We are running this install on an Amazon EC3, so there is some tighter security/setup than I am used to, so I'm pretty sure it has something to do with permissions, and with the basic things that the WP BS plugin does when "securing site from basic attacks".

I feel like it may have something to do with the .htaccess but I don't know where to start.

Thanks for help.