Pro Site new user/site setup error

I setup Word Press MU, (edited config uploaded edited files etc.) added the Pro Sites plugin. Setup everything that was needed to be setup. The error I get is when I go to the new user/site IE testblog.domain.com the web page does not load not even a 404 error page. It is as if that site does not exist on the network or server. Even from the activation email that is sent and I click the link to activate account I get an error.

Any tips of trouble shooting or possible step I may have missed in order to fix this problem?