Progression of Plugins/Sites for Multisite like Edublogs

Has anyone come up with a good post or diagram explaining the progression of plugin installations and development if wanting to build a WordPress Multisite like Edublogs?

Does it matter if one plugin is installed before another? Is there a certain time when the "Sites" that will be duplicated should be created?

Any other advice on the process would be appreciated. I am working on a Multisite with Pro Sites and want to make sure I am headed in the right direction.