Recommendations on Image Management

Hello all. I am pretty unimpressed by most image management plugins out there for WordPress. I see the WPMU DEV generally steers clear of media related plugins. We have tried some plugins on Code Canyon, but have gotten burned on both with incompatible code… Next Gen is also not quite up to par as far as displaying galleries and albums go.

What does everyone usually use here? I usually need something that is highly styleable and responsive if possible. It would be great if it also had a nice clean backend for clients to use.