Running a WP multisite on a subdomain – Issues?

Hi,

I would like to run different WordPress multisite networks on the same server and under the same domain, i.e. :

network1.example.com

network2.example.com

network3.example.com

Are there specific issues and/or limitations with this kind of setup (WPMS running on subdomains)? And what’s about your plugins (specifically plugins like multidb, domain mapping, post indexer)?

Thank you.

Laurent