Running WPMU on WAMP

Our non-profit organisation wants to start a blog network focused on the culture sector.

We have a dedicated windows server/Intel Dual core 2.40 GHz/4gb Ram/Win2008 Web/.NET 2.0./SQL 2005 Standard.

I understand that it is possible to run WPMU on WAMP, although it is not the best arrangement. If the blog network shows promise, I hope to get funds for a Linux server.

I'd be very interested in other experiences with WAMP. Are there any alternatives to WAMP? ZEND?

Also, we would like assistance setting up WPMU on our server. I looked at WP.MU but it appears to only setup at psekhosting.

Thank you.