Safe to replace Wordfence with Defender and Hummingbird?

Hi there,

I would like to know if this is a safe resolution;
I'm running a multisite with Wordfence for the security and caching/performance of the network. I'm curious if its safe to replace the Wordfence plugin with Defender and Hummingbird? Or shall I say is it wise to do this in an early stage?

Please advice.
Kind regards,

Ronald