Security measures for Network Admin Multisite/Buddypress

I’m used to using an IP Lock on my wp-admin directory to limit the admin area to certain IP addresses; however, this is the first time I’ve used a multisite/buddypress set-up in WordPress and I’m uncertain of what the implications are… if I set up a whitelist of IP addresses for my superadmins, will this not lock out admins of blog sites on the network. I’m a bit confused about what to do for the best and any advice, much appreciated.

Cheers, M