Security Tweaks within Defender Pro don't stay

I am reviewing Defender Pro and on the Dashboard I have 7 security tweaks. I have gone through each one to update as recommended and receive a message that the issue has been resolved, however, when I log out and then back in, the issues reappear. I have granted access to my site and I am wondering if you could go through to determine why the fixes aren’t “sticking.” Thank you in advance for your help.
Warm Regards,
Kara