Send post created in Word to Wordpress

My client wants to write his posts in Word as he is much more comfortable working there. I understand Word has a Post te,plate and that the file transfer is done via XML-RPC. I currently have XML-RPC disabled on my multisite.
1. Can I enable XML-RPC on my multisite without breaking anything?
2. Is this process the best way so set up Word -> Wordpress blogging?
Thanks for your insights and help with this.