Should i remove it or not ? define( 'DOMAIN_CURRENT_SITE',

Should i remove it or not ?

define( 'DOMAIN_CURRENT_SITE', 'www.example.com' );
define( 'PATH_CURRENT_SITE', '/' );
define( 'SITE_ID_CURRENT_SITE', 1 );
define( 'BLOG_ID_CURRENT_SITE', 1 );