[Smush Pro] Make Smush Pro CDN works for my site!

I’d like to enable Smush Pro CDN functionality on my site. I’ve additional features related to Speed Optimization installed on site, like Offload Media Plugin using S3 and Cloudfront.
How can I still have taking advantage of those tools along with Smush Pro CDN?
When I turn on Smush Pro CDN all images on my site disappear.