Sub-Site Admin Faiures

Hi all, can you help please? in the last ten minutes my subsite admin access is failing "Internal Server Error" "The server encountered an internal error or misconfiguration and was unable to complete your request."
My network admin is still working for super admin. The sub-site web pages and membership pro users are still working but the admin access to the sub-sites for each admin is failing.
Any ideas? The multi-site concerned is enabled for your access.
Thanks