Sunrise php warning - Cannot modify header information

Hey Guys, I have a clean WPMU Install with only the Domain Mapping plugin installed. Everything works great including the mapping. When I enable WP_DEBUG, I’m getting 1 notice and 2 warnings (see below). Should I be concerned about these?
Notice: Constant COOKIE_DOMAIN already defined in /home/wow123/public_html/wp-content/sunrise.php on line 34
Warning: Cannot modify header information - headers already sent by (output started at /home/wow123/public_html/wp-content/sunrise.php:34) in /home/wow123/public_html/wp-includes/option.php on line 747
Warning: Cannot modify header information - headers already sent by (output started at /home/wow123/public_html/wp-content/sunrise.php:34) in /home/wow123/public_html/wp-includes/option.php on line 748
Thanks,
Dana